Bonn's outstanding scientific institutions include the Center of Advanced European Studies and Research (CAESAR) and the Bonn Science and Research Centre (Wissenschaftszentrum Bonn). The technology and research sector in the region does also include German Aerospace Center (Deutsches Zentrum für Luft- und Raumfahrt, DLR) as well as a number of scientific and research institutes, such as Life & Brain, a centre of excellence in the field of biomedicine.

Two future-oriented institutes have been affiliated to the University: The Center for Development Research (ZEF) is dedicated to education and advisory activities for development policy and practice. The ZEF is also the campus for the "Right Livelihood College". This international educational institution, home to the "Alternative Nobel Prize", supports exchange between prize winners and young scientists from developing and emerging countries. The Center for European Integration Studies (ZEI) accompanies the progress towards European unification. The ZEF and ZEI institutes also offer postgraduate study courses.

The Nees Institute for Biodiversity of Plants is also affiliated with the University of Bonn, providing research and education on an international level. The Zoological Research Museum Alexander Koenig (ZFMK) promotes the next generation of researchers from all over the world, in particular Africa, and is an important scientific partner for the global biodiversity strategy.

Bonn is also home to the German Academic Exchange Service (DAAD) and the Alexander von Humboldt Foundation (AvH).

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